Table 2.
ROC curve results of survival related factors in predicting 5 year survival.
| Cancer type | Events | Cut-off | Sensitivity | Specificity | AUC | 95% CI lower | 95% CI upper | P-value |
|---|---|---|---|---|---|---|---|---|
| KIRC | ||||||||
| Top10_KIRC | −53.062 | 0.748 | 0.641 | 0.748 | 0.696 | 0.800 | <0.05 | |
| C4orf19_AT_5 | 0.759 | 0.646 | 0.627 | 0.681 | 0.625 | 0.737 | <0.05 | |
| EPC2_AT_15 | 0.864 | 0.490 | 0.809 | 0.671 | 0.614 | 0.728 | <0.05 | |
| SCP2_ES_12 | 0.412 | 0.585 | 0.714 | 0.682 | 0.626 | 0.738 | <0.05 | |
| FAM120C_AT_17 | 0.530 | 0.442 | 0.841 | 0.666 | 0.609 | 0.723 | <0.05 | |
| PCMTD1_AT_8 | 0.963 | 0.578 | 0.695 | 0.649 | 0.589 | 0.708 | <0.05 | |
| ZNF814_AT_4.2 | 0.194 | 0.646 | 0.664 | 0.673 | 0.615 | 0.730 | <0.05 | |
| INPP4B_AT_35 | 0.943 | 0.701 | 0.573 | 0.669 | 0.612 | 0.725 | <0.05 | |
| FAM72A_AT_6 | 0.420 | 0.667 | 0.686 | 0.702 | 0.647 | 0.756 | <0.05 | |
| HAGH_ES_6 | 0.986 | 0.673 | 0.573 | 0.644 | 0.587 | 0.701 | <0.05 | |
| TAF1D_RI_12.4 | 0.271 | 0.565 | 0.732 | 0.666 | 0.608 | 0.724 | <0.05 | |
| Predicted probability | 0.520 | 0.537 | 0.909 | 0.754 | 0.701 | 0.806 | <0.05 | |
| KICH | ||||||||
| Top10_KICH | −248.082 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | <0.05 | |
| TATDN1_AD_4.2 | 0.268 | 0.750 | 0.895 | 0.862 | 0.709 | 1.000 | <0.05 | |
| FAM195A_ES_3 | 0.615 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | <0.05 | |
| PLEKHB2_AD_8.2 | 0.170 | 0.750 | 0.842 | 0.868 | 0.722 | 1.000 | <0.05 | |
| TATDN1_ES_3 | 0.918 | 0.875 | 0.895 | 0.888 | 0.725 | 1.000 | <0.05 | |
| DPM3_AP_1 | 0.972 | 0.625 | 0.842 | 0.730 | 0.524 | 0.936 | 0.063 | |
| PEX16_ES_4 | 0.024 | 0.875 | 0.895 | 0.931 | 0.837 | 1.000 | <0.05 | |
| DEPDC5_AT_46 | 0.978 | 0.625 | 0.842 | 0.763 | 0.576 | 0.950 | <0.05 | |
| BCL2L13_ES_7 | 0.822 | 0.875 | 0.947 | 0.921 | 0.810 | 1.000 | <0.05 | |
| MRPS24_RI_1.2 | 0.104 | 1.000 | 0.737 | 0.836 | 0.684 | 0.987 | <0.05 | |
| UBAP2L_AT_29 | 0.392 | 1.000 | 0.895 | 0.987 | 0.953 | 1.000 | <0.05 | |
| Predicted probability | 0.500 | 1.000 | 1.000 | 1.000 | 1.000 | 1.000 | <0.05 | |
| KIRP | ||||||||
| Top10_KIRP | −375.499 | 0.816 | 0.724 | 0.817 | 0.734 | 0.901 | <0.05 | |
| COPE_ES_4 | 0.992 | 0.500 | 0.859 | 0.671 | 0.560 | 0.782 | <0.05 | |
| PPP1CA_ES_2.2 | 0.979 | 0.474 | 0.870 | 0.683 | 0.580 | 0.787 | <0.05 | |
| RBM39_AT_24 | 0.975 | 0.447 | 0.886 | 0.706 | 0.612 | 0.801 | <0.05 | |
| PKIG_ES_2.2 | 0.181 | 0.816 | 0.562 | 0.716 | 0.622 | 0.810 | <0.05 | |
| CLDN11_AT_3 | 0.189 | 0.684 | 0.773 | 0.753 | 0.650 | 0.856 | <0.05 | |
| FKBP8_AA_6.1 | 0.690 | 0.579 | 0.751 | 0.704 | 0.611 | 0.797 | <0.05 | |
| GLS_AT_20 | 0.734 | 0.658 | 0.708 | 0.688 | 0.584 | 0.792 | <0.05 | |
| GUK1_AA_7.1 | 0.962 | 0.658 | 0.686 | 0.702 | 0.610 | 0.794 | <0.05 | |
| KIF4A_AT_32 | 0.641 | 0.553 | 0.924 | 0.730 | 0.628 | 0.832 | <0.05 | |
| AUH_AT_11 | 0.876 | 0.579 | 0.816 | 0.698 | 0.598 | 0.798 | <0.05 | |
| Predicted probability | 0.143 | 0.789 | 0.784 | 0.841 | 0.768 | 0.915 | <0.05 | |
Events are identified as symbol_splice type_exons. Top10_KIRC means the weighted PSI value of the top10 significant SREs in KIRC. Top10_KICH means the weighted PSI value of the top10 significant SREs in KICH. Top10_KIRP means the weighted PSI value of the top10 significant SREs in KIRP.AUC, area under the ROC curve; CI, confidence interval.