Table 5.
Cancer type | Events | Cut-off | Sensitivity | Specificity | AUC | 95% CI lower | 95% CI upper | P-value | |
---|---|---|---|---|---|---|---|---|---|
KIRC | |||||||||
Top10_KIRC | −55.416 | 0.827 | 0.806 | 0.887 | 0.851 | 0.923 | <0.05 | ||
C4orf19_AT_5_AT_51R | 0.855 | 0.745 | 0.917 | 0.881 | 0.849 | 0.913 | <0.05 | ||
EPC2_AT_15 | 0.915 | 0.752 | 0.389 | 0.552 | 0.477 | 0.628 | 0.150 | ||
SCP2_ES_12 | 0.231 | 0.906 | 0.875 | 0.939 | 0.912 | 0.966 | <0.05 | ||
FAM120C_AT_17 | 0.756 | 0.767 | 0.903 | 0.892 | 0.862 | 0.921 | <0.05 | ||
PCMTD1_AT_8 | 0.982 | 0.771 | 0.833 | 0.862 | 0.826 | 0.898 | <0.05 | ||
ZNF814_AT_4.2 | 0.129 | 0.795 | 0.861 | 0.883 | 0.848 | 0.919 | <0.05 | ||
INPP4B_AT_35 | 0.957 | 0.368 | 0.819 | 0.549 | 0.487 | 0.611 | 0.175 | ||
FAM72A_AT_6 | 0.361 | 0.674 | 0.611 | 0.655 | 0.585 | 0.725 | <0.05 | ||
HAGH_ES_6 | 0.986 | 0.523 | 0.708 | 0.605 | 0.545 | 0.665 | <0.05 | ||
TAF1D_RI_12.4 | 0.238 | 0.402 | 0.889 | 0.629 | 0.577 | 0.681 | <0.05 | ||
Predicted probability | 0.834 | 0.955 | 0.931 | 0.988 | 0.978 | 0.998 | <0.05 | ||
KICH | |||||||||
Top10_KICH | −247.040 | 0.455 | 0.880 | 0.688 | 0.576 | 0.800 | 0.006 | ||
TATDN1_AD_4.2 | 0.188 | 0.636 | 0.840 | 0.765 | 0.668 | 0.861 | <0.05 | ||
FAM195A_ES_3 | 0.655 | 0.409 | 0.760 | 0.552 | 0.421 | 0.683 | 0.444 | ||
PLEKHB2_AD_8.2 | 0.142 | 0.682 | 0.520 | 0.557 | 0.428 | 0.686 | 0.401 | ||
TATDN1_ES_3 | 0.938 | 0.470 | 0.760 | 0.603 | 0.476 | 0.730 | 0.131 | ||
DPM3_AP_1 | 0.947 | 0.955 | 0.320 | 0.598 | 0.462 | 0.735 | 0.149 | ||
PEX16_ES_4 | 0.020 | 0.576 | 0.560 | 0.535 | 0.404 | 0.666 | 0.606 | ||
DEPDC5_AT_46 | 0.985 | 0.727 | 0.640 | 0.656 | 0.524 | 0.788 | <0.05 | ||
BCL2L13_ES_7 | 0.892 | 0.879 | 0.920 | 0.940 | 0.891 | 0.989 | <0.05 | ||
MRPS24_RI_1.2 | 0.097 | 0.561 | 0.880 | 0.683 | 0.578 | 0.789 | <0.05 | ||
UBAP2L_AT_29 | 0.382 | 0.364 | 0.920 | 0.593 | 0.479 | 0.707 | 0.174 | ||
Predicted probability | 0.614 | 0.955 | 0.920 | 0.970 | 0.936 | 1.000 | <0.05 | ||
KIRP | |||||||||
Top10_KIRP | −375.286 | 0.341 | 0.906 | 0.502 | 0.425 | 0.571 | 0.973 | ||
COPE_ES_4 | 0.996 | 0.562 | 0.844 | 0.735 | 0.651 | 0.819 | <0.05 | ||
PPP1CA_ES_2.2 | 0.989 | 0.614 | 0.813 | 0.697 | 0.622 | 0.772 | <0.05 | ||
RBM39_AT_24 | 0.983 | 0.648 | 0.844 | 0.737 | 0.664 | 0.809 | <0.05 | ||
PKIG_ES_2.2 | 0.187 | 0.531 | 0.906 | 0.701 | 0.627 | 0.776 | <0.05 | ||
CLDN11_AT_3 | 0.261 | 0.779 | 1.000 | 0.918 | 0.886 | 0.951 | <0.05 | ||
FKBP8_AA_6.1 | 0.723 | 0.779 | 0.844 | 0.839 | 0.774 | 0.904 | <0.05 | ||
GLS_AT_20 | 0.873 | 0.859 | 0.531 | 0.723 | 0.622 | 0.824 | <0.05 | ||
GUK1_AA_7.1 | 0.964 | 0.431 | 0.719 | 0.534 | 0.443 | 0.625 | 0.527 | ||
KIF4A_AT_32 | 0.210 | 0.741 | 0.813 | 0.829 | 0.763 | 0.895 | <0.05 | ||
AUH_AT_11 | 0.890 | 0.334 | 0.969 | 0.618 | 0.539 | 0.696 | <0.05 | ||
Predicted probability | 0.923 | 0.979 | 1.000 | 0.999 | 0.997 | 1.000 | <0.05 |
Events are identified as symbol_splice type_exons. Top10_KIRC means the weighted PSI value of the top10 significant SREs in KIRC. Top10_KICH means the weighted PSI value of the top10 significant SREs in KICH. Top10_KIRP means the weighted PSI value of the top10 significant SREs in KIRP.AUC, area under the ROC curve; CI, confidence interval.