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. 2019 Nov 27;9:1317. doi: 10.3389/fonc.2019.01317

Table 5.

ROC curve results of survival related factors in predicting diagnostic test.

Cancer type Events Cut-off Sensitivity Specificity AUC 95% CI lower 95% CI upper P-value
KIRC
Top10_KIRC −55.416 0.827 0.806 0.887 0.851 0.923 <0.05
C4orf19_AT_5_AT_51R 0.855 0.745 0.917 0.881 0.849 0.913 <0.05
EPC2_AT_15 0.915 0.752 0.389 0.552 0.477 0.628 0.150
SCP2_ES_12 0.231 0.906 0.875 0.939 0.912 0.966 <0.05
FAM120C_AT_17 0.756 0.767 0.903 0.892 0.862 0.921 <0.05
PCMTD1_AT_8 0.982 0.771 0.833 0.862 0.826 0.898 <0.05
ZNF814_AT_4.2 0.129 0.795 0.861 0.883 0.848 0.919 <0.05
INPP4B_AT_35 0.957 0.368 0.819 0.549 0.487 0.611 0.175
FAM72A_AT_6 0.361 0.674 0.611 0.655 0.585 0.725 <0.05
HAGH_ES_6 0.986 0.523 0.708 0.605 0.545 0.665 <0.05
TAF1D_RI_12.4 0.238 0.402 0.889 0.629 0.577 0.681 <0.05
Predicted probability 0.834 0.955 0.931 0.988 0.978 0.998 <0.05
KICH
Top10_KICH −247.040 0.455 0.880 0.688 0.576 0.800 0.006
TATDN1_AD_4.2 0.188 0.636 0.840 0.765 0.668 0.861 <0.05
FAM195A_ES_3 0.655 0.409 0.760 0.552 0.421 0.683 0.444
PLEKHB2_AD_8.2 0.142 0.682 0.520 0.557 0.428 0.686 0.401
TATDN1_ES_3 0.938 0.470 0.760 0.603 0.476 0.730 0.131
DPM3_AP_1 0.947 0.955 0.320 0.598 0.462 0.735 0.149
PEX16_ES_4 0.020 0.576 0.560 0.535 0.404 0.666 0.606
DEPDC5_AT_46 0.985 0.727 0.640 0.656 0.524 0.788 <0.05
BCL2L13_ES_7 0.892 0.879 0.920 0.940 0.891 0.989 <0.05
MRPS24_RI_1.2 0.097 0.561 0.880 0.683 0.578 0.789 <0.05
UBAP2L_AT_29 0.382 0.364 0.920 0.593 0.479 0.707 0.174
Predicted probability 0.614 0.955 0.920 0.970 0.936 1.000 <0.05
KIRP
Top10_KIRP −375.286 0.341 0.906 0.502 0.425 0.571 0.973
COPE_ES_4 0.996 0.562 0.844 0.735 0.651 0.819 <0.05
PPP1CA_ES_2.2 0.989 0.614 0.813 0.697 0.622 0.772 <0.05
RBM39_AT_24 0.983 0.648 0.844 0.737 0.664 0.809 <0.05
PKIG_ES_2.2 0.187 0.531 0.906 0.701 0.627 0.776 <0.05
CLDN11_AT_3 0.261 0.779 1.000 0.918 0.886 0.951 <0.05
FKBP8_AA_6.1 0.723 0.779 0.844 0.839 0.774 0.904 <0.05
GLS_AT_20 0.873 0.859 0.531 0.723 0.622 0.824 <0.05
GUK1_AA_7.1 0.964 0.431 0.719 0.534 0.443 0.625 0.527
KIF4A_AT_32 0.210 0.741 0.813 0.829 0.763 0.895 <0.05
AUH_AT_11 0.890 0.334 0.969 0.618 0.539 0.696 <0.05
Predicted probability 0.923 0.979 1.000 0.999 0.997 1.000 <0.05

Events are identified as symbol_splice type_exons. Top10_KIRC means the weighted PSI value of the top10 significant SREs in KIRC. Top10_KICH means the weighted PSI value of the top10 significant SREs in KICH. Top10_KIRP means the weighted PSI value of the top10 significant SREs in KIRP.AUC, area under the ROC curve; CI, confidence interval.