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. 2019 Dec 3;7:315. doi: 10.3389/fcell.2019.00315

FIGURE 2.

FIGURE 2

Exosomes from the immune system affect cardiac tissue. Immune system is modulated under different metabolic settings including diabetes, obesity, fatty liver and metabolic syndromes. The role of exosomes secreted by immune cells under these conditions in heart pathology is yet to be fully described. It is also not known whether the beneficial effects of stem cell-based therapies in heart diseases are mediated by immune modulation that may lead to the release of cardio protective exosomes.