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. 2019 Dec 3;13:263. doi: 10.3389/fnbeh.2019.00263

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Copyright © 2019 Krakenberg, von Kortzfleisch, Kaiser, Sachser and Richter.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Anxiety-like behavior. (A) Time on open arms of Elevated plus maze, (B) time in center of Open field test, (C) time in light compartment of Dark light test, and (D) latency to enter arena of Free exploration test, displayed by 5-HTT +/+, 5-HTT +/−, and 5-HTT −/− mice. Data are presented as means ± SEM. Statistics: LMM; post hoc testing: Tukey’s test. Sample sizes: EPM, DL: n+/+ = 15, n+/− = 14, n−/− = 11. OF: n+/+ = 14, n+/− = 14, n−/− = 11. FE: n+/+ = 15, n+/− = 13 n−/− = 11. ^∗∗∗p ≤ 0.001, ^∗∗p ≤ 0.01, ^∗p ≤ 0.05, t = p ≤ 0.1.