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. 2019 Dec 3;10:2777. doi: 10.3389/fimmu.2019.02777

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Copyright © 2019 Saadalla, Lima, Tsai, Osman, Singh, Linden, Dennis, Haeryfar, Gurish, Gounari and Khazaie.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Quantitation of mast cells in colon polyps of 5CreCAT mice. (A–C) Distribution of MCs expressing mMCP2, 5 or 6 in colon adenomas of 5CreCAT mice; 200X field, n = 5 mice; plots show all mast cells (all), intraepithelial mast cells (IE), and stromal mast cells (stromal); unpaired Student's t-test. (A) Densities of MCs expressing mMCP2, 5, or 6 in spontaneous colon polyps; n = 5 mice. (B) Densities of MCs in distant healthy colon; n = 4 mice. (C) Representative MC stains in serial sections of 5CreCAT colon-adenomas, for mMCP2, 5, or 6.