Table 1. Odds Ratios of Neonatal Death Among 868 617 Infants Without Congenital Malformations According to Gestational Age–Specific Quartiles of Placental Weight, Birth Weight, and Placental to Birth Weight Ratioa.
| Quartile | Neonatal Death | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Placental Weight | Birth Weight | Placental to Birth Weight Ratio | ||||||||||
| No. | OR (95% CI) | No. | OR (95% CI) | No. | OR (95% CI) | |||||||
| Yes | No | Crude | Adjusted | Yes | No | Crude | Adjusted | Yes | No | Crude | Adjusted | |
| Gestational Age, 29-36 wk (n = 39 641) | ||||||||||||
| First | 41 | 9345 | 1.45 (0.98-2.16) | 1.56 (1.05-2.32) | 42 | 9668 | 1.14 (0.78-1.67) | 1.29 (0.87-1.90) | 29 | 9936 | 0.79 (0.51-1.21) | 0.78 (0.51-1.21) |
| Second to third | 62 | 20 535 | 1 [Reference] | 1 [Reference] | 76 | 20 020 | 1 [Reference] | 1 [Reference] | 74 | 19 934 | 1 [Reference] | 1 [Reference] |
| Fourth | 69 | 9589 | 2.38 (1.69-3.36) | 2.31 (1.63-3.27) | 54 | 9781 | 1.45 (1.03-2.06) | 1.38 (0.97-1.97) | 69 | 9599 | 1.94 (1.39-2.69) | 1.94 (1.40-2.70) |
| Gestational Age, 37-42 wk (n = 828 976) | ||||||||||||
| First | 89 | 204 898 | 1.18 (0.91-1.54) | 1.18 (0.90-1.53) | 116 | 206 442 | 1.95 (1.51-2.52) | 1.90 (1.47-2.45) | 80 | 207 495 | 1.07 (0.82-1.41) | 1.09 (0.83-1.43) |
| Second to third | 151 | 411 649 | 1 [Reference] | 1 [Reference] | 120 | 416 265 | 1 [Reference] | 1 [Reference] | 149 | 414 620 | 1 [Reference] | 1 [Reference] |
| Fourth | 80 | 212 109 | 1.03 (0.78-1.35) | 1.03 (0.78-1.35) | 84 | 205 949 | 1.42 (1.07-1.87) | 1.43 (1.08-1.90) | 91 | 206 541 | 1.23 (0.96-1.59) | 1.20 (0.93-1.56) |
Abbreviation: OR, odds ratio.
a
Adjustments were made for offspring sex, parity (0 or ≥1), pregnancy after in vitro fertilization (yes/no), maternal age (years), maternal smoking (yes/no), preeclampsia (yes/no), and maternal diabetes (yes/no).