Fig E1.

EAT enrollment and randomization. Baseline visits occurred when participants were 3 months of age. *Eight infants randomized to each group were found to have significant health issues either on blood testing or on clinical examination at the enrollment visit, rendering them ineligible for enrollment: conditions included severe vitamin D deficiency, severe iron deficiency, severe failure to thrive, familial hypercholesterolemia, congenital stridor, epidermolysis bullosa, and cartilage-hair hypoplasia syndrome. †Forty-three participants in the SIG and 69 participants in the EIG withdrew voluntarily from the study. Reasons given were as follows: concerns about blood tests (SIG, 0; EIG, 2), emigration (SIG, 10; EIG, 12), expenses (SIG, 1; EIG, 1), family health issues (SIG, 3; EIG, 0), family issues (SIG, 2; EIG, 4), no reason given (SIG, 11; EIG, 16), lost contact with family (SIG, 15; EIG, 28), too far to travel for study assessments (SIG, 0; EIG, 1), and unhappy participating in the study (SIG, 1; EIG, 5).