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. 2019 Nov 20;10:1162. doi: 10.3389/fgene.2019.01162

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Copyright © 2019 Chai, DiAdamo, Grommisch, Xu, Zhou, Wen, Mahoney, Bale, McGrath, Spencer-Manzon, Li and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The prenatal and pediatric caseloads during 2008–2017. (A) The total number of cases and (B) the annual number of cases analyzed by karyotyping, aCGH, and FISH in the prenatal setting. (C) The total number of cases and (D) the annual number of cases analyzed by karyotyping, aCGH and FISH in the pediatric setting. aCGH, array comparative genomic hybridization; FISH, fluorescence in situ hybridization.