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. 2019 Nov 20;10:1162. doi: 10.3389/fgene.2019.01162

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Copyright © 2019 Chai, DiAdamo, Grommisch, Xu, Zhou, Wen, Mahoney, Bale, McGrath, Spencer-Manzon, Li and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation of prevalence with abnormal detection rate in pediatric setting by linear regression analysis. (A) Abnormality detection rate in pediatric setting was plotted against the reported prevalence for DGS/VCFS (velocardiofacial syndrome), WBS (Williams-Beuren syndrome), PWS/AS (Prader-Willi/Angelman syndromes), SMS (Smith-Magenis syndrome), and HNPP (hereditary neuropathy with liability to pressure palsies). (B) Abnormality detection rate in pediatric setting was plotted against the reported incidences for common aneuploidies trisomy 21, 45,X, trisomy 18, and trisomy 13.