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. 2019 Dec 5;14:2787–2798. doi: 10.2147/COPD.S225694

Table 3.

Peak Parameters Of The Constant Work Rate Exercise Test After 12 Weeks Of Acupuncture Treatment And Follow-Up Data

Week 0 (n=16) Week 12 (n=16) Week 16 (n=14) Week 24 (n=13) p-Value (F-Value)a
Endurance time, s 810 (470) 1125 (657)*** 1068 (714) 1046 (691) 0.001 (7.121)
Inline graphicO2, mL ⋅ kg−1 ⋅ min−1 13.8 (2.8) 12.9 (2.3)* 13.2 (2.7) 13.6 (3.1) 0.038 (3.079)
Inline graphicO2, mL ⋅ min−1 822 (176) 771 (149)* 772 (162) 807 (182) 0.045 (2.924)
Inline graphicCO2, mL ⋅ min−1 798 (170) 753 (136) 759 (149) 768 (175) 0.174 (1.739)
Dyspnoea, Borg scale 6.2 (1.9) 6.2 (2.5) 5.9 (2.8) 6.5 (2.4) 0.451 (0.897)
Leg fatigue, Borg scale 5.5 (2.4) 5.3 (2.8) 5.4 (3.1) 5.3 (3.3) 0.977 (0.068)
Inline graphicTe, L 1.30 (0.31) 1.20 (0.27)** 1.22 (0.30) 1.23 (0.30) 0.014 (4.021)
Inline graphicTi - Inline graphicTe, mL 22.3 (14.9) 8.1 (26.5) 5.4 (29.4) 14.9 (19.8) 0.159 (1.823)
fR, breaths ⋅ min−1 28.1 (5.7) 30.4 (6.3)* 28.3 (5.1) 28.4 (4.3) 0.049 (2.865)
Inline graphicE, L ⋅ min−1 35.7 (8.1) 34.7 (6.0) 33.8 (7.4) 34.4 (8.7) 0.589 (0.648)
Inline graphicD/Inline graphicT 0.37 (0.04) 0.38 (0.05) 0.37 (0.04) 0.37 (0.04) 0.372 (1.071)
Inline graphicE/Inline graphicO2 43.7 (6.4) 45.9 (8.1) 44.4 (8.4) 43.4 (8.7) 0.061 (2.660)
Inline graphicE/Inline graphicCO2 44.9 (5.8) 46.7 (6.8) 45.0 (7.0) 45.4 (8.0) 0.189 (1.669)
HR, beats ⋅ min−1 121 (12) 123 (14) 124 (11) 123 (11) 0.592 (0.749)
SpO2, % 91.6 (4.1) 90.9 (4.8) 90.1 (4.9) 88.9 (4.7) 0.023 (3.556)
DFO2, % 2.83 (0.39) 2.69 (0.42)* 2.80 (0.48) 2.87 (0.59) 0.100 (2.226)
PETCO2, mmHg 34.1 (4.7) 33.6 (5.2) 34.5 (5.4) 34.1 (6.2) 0.288 (1.298)
FeCO2, % 3.01 (0.39) 2.91 (0.40) 3.02 (0.43) 2.98 (0.49) 0.191 (1.661)

Notes: ATS/ERS Statement on respiratory muscle testing. Am J Respir Crit Care Med Data are presented as the mean (standard deviation). Treatment effect: mean difference from pre-treatment; *P < 0.05, **P < 0.01, ***P < 0.001: pre-treatment vs 12 weeks, paired t-test. aTime course effect of 12-week acupuncture treatment by one-way repeated measures analysis of variance.

Abbreviations: DFO2, difference between fractional content of inspired oxygen and fractional content of expired oxygen; FeCO2, fractional content of expired carbon dioxide; fR, breathing frequency; HR, heart rate; PETCO2, end-tidal partial pressure of CO2; SpO2, saturation pulse oxygenation; Inline graphicD/Inline graphicT, dead space/tidal volume ratio; Inline graphicE, minute ventilation; Inline graphicCO2, CO2 output; Inline graphicO2, oxygen uptake; Inline graphicT, tidal volume; Inline graphicTi - Inline graphicTe, inspiratory tidal volume - expiratory tidal volume.