Table 2.
Perioperative variables of hemodynamic parameters.
| Time | Sham | Dex | Oxy | |
|---|---|---|---|---|
| HR, median (Min, Max)(IQR) beats.min-1 | T0 | 69 (60, 89) (66–77) | 73 (60, 86) (61–81) | 70 (52, 85) (63–79) |
| T1 | 69 (55, 78) (64–73) | 60 (49, 70) (52–64) | 66 (54, 80) (56–73) | |
| T2 | 70 (56, 80) (66–72) | 60 (50, 71) (55–66) | 67 (52, 83) (57–71) | |
| T3 | 68 (55, 81) (64–70) | 59 (51, 71) (55–64) | 65 (53, 80) (58–71) | |
| T4 | 68 (58, 83) (65–70) | 60 (47, 72) (55–66) | 68 (56, 77) (61–72) | |
| T5 | 69 (55, 84) (67–71) | 60 (49, 70) (55–66) | 69 (61, 85) (65–74) | |
| T6 | 71 (60, 81) (68–76) | 61 (47, 76) (55–67) | 70 (53, 86) (67–76) | |
| T7 | 76 (63, 87) (68–81) | 66 (52, 78) (63–72) | 77 (65, 93) (71–81) | |
| SAP, median (Min, Max)(IQR) mmHg | T0 | 144 (129, 153) (138–149) | 139 (109, 169) (135–146) | 139 (123, 164) (130–146) |
| T1 | 127 (115, 138) (122–129) | 130 (109, 157) (119–139) | 130 (105, 164) (121–136) | |
| T2 | 130 (120, 142) (127–134) | 131 (102, 156) (121–142) | 128 (115, 137) (122–130) | |
| T3 | 133 (128, 148) (130–139) | 127 (100, 162) (118–142) | 123 (117, 135) (120–128) | |
| T4 | 136 (115, 148) (133–144) | 127 (100, 167) (117–135) | 124 (100, 138) (120–129) | |
| T5 | 139 (114, 148) (136–142) | 127 (98, 151) (112–133) | 127 (113, 136) (124–131) | |
| T6 | 142 (121, 150) (137–144) | 125 (105, 158) (115–132) | 134 (118, 145) (128–139) | |
| T7 | 136 (120, 150) (132–141) | 115 (95, 140) (106–127) | 128 (116, 140) (122–131) | |
| MAP, median (Min, Max)(IQR) mmHg | T0 | 94 (82, 108) (90–99) | 92 (83, 118) (90–98) | 91 (82, 110) (88–99) |
| T1 | 84 (78, 92) (83–89) | 88 (77, 109) (85–92) | 90 (72, 101) (81–93) | |
| T2 | 87 (81, 93) (85–89) | 90 (75, 115) (87–94) | 88 (75, 98) (85–93) | |
| T3 | 90 (83, 96) (85–92) | 89 (73, 111) (85–91) | 86 (78, 97) (83–88) | |
| T4 | 92 (74, 97) (88–94) | 88 (72, 114) (84–94) | 84 (74, 98) (81–86) | |
| T5 | 92 (75, 99) (89–96) | 89 (69, 108) (84–90) | 87 (78, 94) (83–88) | |
| T6 | 94 (78, 99) (92–96) | 87 (71, 114) (85–90) | 92 (82, 96) (89–93) | |
| T7 | 87 (84, 93) (85–91) | 81 (67, 99) (74–84) | 84 (77, 90) (81–85) | |
| DAP, median (Min, Max)(IQR) mmHg | T0 | 69 (58, 86) (63–76) | 70 (60, 92) (68–77) | 69 (60, 90) (65–73) |
| T1 | 64 (59, 73) (61–69) | 68 (58, 89) (65–73) | 69 (50, 80) (63–74) | |
| T2 | 65 (58, 75) (61–68) | 70 (62, 94) (65–73) | 70 (55, 82) (64–75) | |
| T3 | 69 (59, 74) (63–70) | 69 (60, 86) (65–72) | 66 (57, 85) (62–70) | |
| T4 | 68 (53, 77) (66–71) | 70 (57, 87) (66–73) | 63 (57, 79) (61–67) | |
| T5 | 69 (55, 78) (64–73) | 68 (54, 87) (66–71) | 66 (57, 75) (62–70) | |
| T6 | 70 (57, 76) (67–73) | 69 (52, 92) (64–73) | 69 (61, 75) (67–72) | |
| T7 | 63 (60, 70) (61–67) | 60 (50, 78) (58–65) | 62 (55, 66) (60–64) | |
| RPP, median (Min, Max)(IQR) | T0 | 9945 (8220, 13617) (9529–10948) | 9486 (7680, 13520) (8419–11297) | 9860 (7332, 11730) (9280–10465) |
| T1 | 8568 (6820, 10062) (7865–9412) | 7418 (5700, 9928) (6834–8621) | 8665 (5775, 10064) (7859–9383) | |
| T2 | 8967 (7056, 10640) (8462–9625) | 7815 (5406, 10608) (6815–8887) | 8273 (6604, 10956) (7434–8975) | |
| T3 | 8973 (7336, 10368) (8466–9624) | 7620 (5700, 10206) (6621–8793) | 8074 (6519, 10480) (7018–8604) | |
| T4 | 9338 (6670, 11288) (8806–10063) | 7467 (5311, 10521) (6588–8870) | 8404 (6100, 10626) (7464–8865) | |
| T5 | 9862 (7410, 11340) (9163–10024) | 7899 (5390, 9060) (6507–8145) | 8732 (6954, 11424) (8113–9720) | |
| T6 | 9973 (7623, 11232) (9227–10819) | 7605 (5170, 9954) (6773–8359) | 9174 (6254, 12470) (8757–10517) | |
| T7 | 10170 (8448, 12750) (9110–10958) | 7868 (5500, 9933) (6768–8300) | 9532 (7540, 13020) (8965–10670) |
Sham – control (ischemia-reperfusion, I/R) group; Dex – dexmedetomidine group; Oxy – oxycodone group; Min – minimum; Max – maximum; IQR – interquartile range.