Table 3.
Perioperative variables of I/R and immune parameters.
| Time | Sham | Dex | Oxy | |
|---|---|---|---|---|
| MDA, median (Min, Max) (IQR) μmol·L−1 | T0 | 4.16 (2.91, 4.69) (3.92–4.43) | 4.05 (3.02, 5.09) (3.76–4.42) | 4.12 (3.32, 5.38) (3.51–4.83) |
| T8 | 4.66 (3.81, 5.84) (4.25–5.09) | 4.25 (3.03, 5.25) (4.02–4.69) | 4.19 (3.39, 5.18) (3.94–4.63) | |
| T9 | 5.08 (3.94, 6.87) (4.77–5.62) | 4.47 (3.25, 7.00) (3.96–5.00) | 4.55 (3.16, 6.03) (4.23–5.03) | |
| SOD, median (Min, Max)(IQR) U·mL−1 | T0 | 73.18 (53.80, 83.09) (64.36–79.56) | 75.15 (53.65, 88.27) (69.55–77.01) | 70.12 (51.07, 92.25) (64.10–75.01) |
| T8 | 60.14 (44.58, 65.52) (53.54–62.71) | 63.32 (44.40, 82.72) (58.27–70.35) | 64.80 (50.35, 88.10) (59.34–67.89) | |
| T9 | 51.08 (34.25, 61.35) (45.89–54.43) | 56.93 (47.92, 70.84) (50.88–61.43) | 55.54 (50.09, 66.31) (50.73–61.50) | |
| TNF-α, median (Min, Max)(IQR) pg·mL−1 | T0 | 23.08 (15.34, 36.72) (19.79–27.78) | 24.94 (15.68, 31.48) (22.55–28.51) | 22.58 (15.94, 30.09) (20.17–26.70) |
| T8 | 29.79 (18.48, 40.24) (25.96–31.82) | 27.48 (19.07, 35.08) (26.03–30.63) | 23.75 (15.14, 35.33) (18.76–28.35) | |
| T9 | 36.95 (24.52, 47.02) (34.92–41.34) | 30.43 (18.48, 36.35) (25.45–33.11) | 26.81 (12.51, 42.91) (19.78–35.92) | |
| IL-6, median (Min, Max)(IQR) pg·mL−1 | T0 | 6.19 (3.91, 8.53) (4.52–7.51) | 6.43 (4.33, 8.00) (5.28–7.26) | 5.99 (4.08, 7.31) (5.18–6.66) |
| T8 | 8.12 (5.11, 11.71) (6.39–9.88) | 7.15 (6.25, 11.67) (6.65–8.60) | 5.57 (4.64, 9.46) (5.21–6.87) | |
| T9 | 28.34 (19.79, 39.17) (23.11–31.05) | 21.42 (17.73, 27.96) (19.97–25.65) | 18.19 (13.11, 30.80) (14.17–22.65) | |
| FABP3, median (Min, Max)(IQR) ng·mL−1 | T0 | 1.84 (0.95, 2.72) (1.50–2.17) | 1.83 (1.09, 2.66) (1.53–2.27) | 1.93 (1.22, 2.68) (1.65–2.14) |
| T8 | 2.38 (1.51, 3.30) (2.02–2.67) | 2.13 (1.44, 2.83) (1.72–2.53) | 2.10 (1.43, 2.96) (1.89–2.52) | |
| T9 | 2.53 (1.17, 3.72) (2.03–2.92) | 2.29 (1.62, 3.16) (1.69–2.70) | 2.21 (1.62, 2.77) (1.96–2.44) | |
| ET-1, median (Min, Max)(IQR) pg·mL−1 | T0 | 21.82 (15.13, 36.67) (18.77–28.30) | 23.08 (13.57, 41.90) (18.67–28.06) | 23.78 (17.63, 35.16) (19.91–27.91) |
| T8 | 27.59 (19.62, 44.63) (22.91–33.82) | 26.18 (19.32, 41.49) (21.74–29.75) | 28.72 (21.83, 36.80) (25.83–32.31) | |
| T9 | 37.81 (26.18, 50.83) (27.98–45.09) | 27.94 (19.27, 38.47) (23.43–31.27) | 30.22 (20.60, 35.78) (26.92–31.77) | |
| BDNF, median (Min, Max)(IQR) pg·mL−1 | T0 | 217.91 (156.55, 277.28) (203.55–240.34) | 222.34 (150.64, 277.46) (210.32–241.76) | 217.38 (185.56, 267.47) (201.62–239.39) |
| T8 | 219.73 (152.22, 273.12) (195.36–241.60) | 218.01 (181.64, 289.71) (205.81–232.21) | 198.13 (151.64, 251.31) (180.29–208.28) | |
| T9 | 177.03 (132.10, 252.68) (156.91–204.66) | 200.15 (161.17, 304.65) (171.78–227.52) | 174.86 (121.77, 213.91) (164.78–193.38) |
Sham – control (ischemia-reperfusion, I/R) group; Dex – dexmedetomidine group; Oxy – oxycodone group; Min – minimum; Max – maximum; IQR – interquartile range.