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. 2019 Dec 9;19:356. doi: 10.1186/s12906-019-2781-4

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Regulation of activation of the SLAM/SAP signaling pathway after 24 h of treatment. (a) BM cells were stained with CD150/SLAM and SH2D1A/SAP antibodies and observed by confocal immunofluorescence microscopy. The double-stained cells (yellow) were quantified with ImageJ. The scale bar corresponds to 60 μm throughout. (b) The quantified results are presented in a bar chart. a, Normal (N) group; b, Model (M) group; c and f, Radix Astragali (R) group; d and g, Radix Angelicae Sinensis (A) group; e and h, Radix Astragali + Radix Angelicae Sinensis (R + A) group; c, d and e were treated with 100 μg/mL of freeze-dried powders, and f, g and h were treated with 250 μg/mL of freeze-dried powders. Data are presented as the mean ± SD, n = 3. *P < 0.05 and **P < 0.01