Table 2.
Subgroup analysis showing disease-specific risk with VDR TaqI polymorphism
| Model | Type of disease | N | OR | 95% CI | P value |
|---|---|---|---|---|---|
| Allele contrast (A vs. a) | Overall | 16 | 1.11 | [1.0262; 1.1967] | 0.009 |
| ESRD | 2 | 1.17 | [1.0171; 1.3357] | 0.028 | |
| NL | 11 | 1.09 | [0.9673; 1.2356] | 0.153 | |
| DN | 3 | 1.07 | [0.9250; 1.2322] | 0.371 | |
| Recessive model (AA vs. Aa+aa) | Overall | 16 | 1.19 | [0.9266; 1.5392] | 0.170 |
| ESRD | 2 | 1.14 | [0.8497; 1.5235] | 0.386 | |
| NL | 11 | 1.32 | [0.8084; 2.1503] | 0.268 | |
| DN | 3 | 1.11 | [0.8527; 1.4432] | 0.439 | |
| Dominant model (AA+Aa vs. aa) | Overall | 16 | 1.14 | [1.0234; 1.2709] | 0.017 |
| ESRD | 2 | 1.24 | [1.0367; 1.4863] | 0.019 | |
| NL | 11 | 1.09 | [0.9148; 1.2930] | 0.342 | |
| DN | 3 | 1.09 | [0.8737; 1.3505] | 0.456 | |
| Overdominant (Aa vs. AA + aa) | Overall | 16 | 0.99 | [0.8106; 1.2040] | 0.904 |
| ESRD | 2 | 1.19 | [0.9904; 1.4233] | 0.063 | |
| NL | 11 | 0.92 | [0.6575; 1.2975] | 0.647 | |
| DN | 3 | 1.01 | [0.8261; 1.2289] | 0.940 | |
| pairw1 (AA vs. aa) | Overall | 16 | 1.20 | [1.0117; 1.4232] | 0.036 |
| ESRD | 2 | 1.26 | [0.9280; 1.7151] | 0.138 | |
| NL | 11 | 1.23 | [0.9346; 1.6077] | 0.141 | |
| DN | 3 | 1.11 | [0.8081; 1.5149] | 0.528 | |
| pairw2 (AA vs. Aa) | Overall | 16 | 1.16 | [0.8525; 1.5857] | 0.341 |
| ESRD | 2 | 1.01 | [0.7443; 1.3803] | 0.932 | |
| NL | 11 | 1.30 | [0.7200; 2.3483] | 0.384 | |
| DN | 3 | 1.09 | [0.8304; 1.4407] | 0.524 | |
| pairw3 (Aa vs. aa) | Overall | 16 | 1.09 | [0.9167; 1.2888] | 0.337 |
| ESRD | 2 | 1.24 | [1.0233; 1.4966] | 0.028 | |
| NL | 11 | 1.04 | [0.7873; 1.3666] | 0.795 | |
| DN | 3 | 1.07 | [0.8487; 1.3425] | 0.577 |