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. 2019 Dec 10;19:241. doi: 10.1186/s12890-019-1001-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Changes in airway responsiveness according to methacholine concentration in control and OVA-sensitized and challenged mice. a Respiratory system resistance (Rrs) and (b) elastance (E) was measured 24 h after the last OVA challenge in mice. Bars represent the mean ± SEM (n = 5/group). ^#p < 0.05 vs. inhaled saline, ^*p < 0.05 vs. intranasal saline