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. Author manuscript; available in PMC: 2019 Dec 10.
Published in final edited form as: J Intensive Care Med. 2016 Jul 21;32(1):86–94. doi: 10.1177/0885066616658449

Figure 4.

Figure 4.

The spare respiratory capacity (SRC) in 4 patient samples where PBMCs were isolated using a Ficoll gradient and mitochondrial respiration was obtained at baseline and after 100 mmol/L cyanide was added (Oroboros O2K). This illustrates that cyanide (complex IV inhibitor) decreases SRC. Mean data (n = 4) were plotted with +standard error of the mean. *P < .05. All study protocols for collection and handling of human samples were reviewed and approved by the institutional review board, University of Pennsylvania.