. 2019 Sep 16;33(11):12680–12695. doi: 10.1096/fj.201901503R

TABLE 2.

Gene expression data

Gene	7-d Scx:IGF1R⁺	7-d Scx:IGF1R^Δ	14-d Scx:IGF1R⁺	14-d Scx:IGF1R^Δ
CCNA2	8.19 ± 1.90	4.48 ± 0.66^a	3.88 ± 1.27^a	4.38 ± 0.97^a
CCNB1	3.09 ± 0.43	1.81 ± 0.18^a	1.19 ± 0.60^a	1.43 ± 0.36^a
CCND1	3.82 ± 1.40	3.40 ± 0.64	3.00 ± 0.92	3.36 ± 0.53
CCNE1	0.29 ± 0.04	0.23 ± 0.15	0.19 ± 0.02	0.11 ± 0.03^a
CDKN1A	2.07 ± 0.39	3.04 ± 0.85^a	2.23 ± 0.46^b	1.74 ± 0.34^b
COL1A1	224 ± 72.4	372 ± 46.7^a	482 ± 133^a	561 ± 74.5^a^,^b
COL1A2	889 ± 316	1450 ± 159^a	1890 ± 551^a	2270 ± 61.4^a^,^b
COL3A1	1308 ± 346	1490 ± 324	2070 ± 640^a	2250 ± 472^a^,^b
COL4A1	28.8 ± 3.93	35.2 ± 7.87	42.4 ± 11.1^a	46.5 ± 8.06^a^,^b
COL5A1	4.66 ± 1.47	6.56 ± 0.84	7.60 ± 1.13^a^,^c	9.47 ± 1.42^a^,^b
COL6A1	14.2 ± 3.53	32.0 ± 4.57^a	34.1 ± 11.8^a	35.3 ± 5.81^a
EGR1	2.36 ± 0.97	1.75 ± 0.88	1.16 ± 0.50^a	0.93 ± 0.45^a
EGR2	0.17 ± 0.04	0.15 ± 0.07	0.10 ± 0.05^a	0.05 ± 0.01^a^,^b
HAS2	2.19 ± 0.34	0.79 ± 0.11^a	1.20 ± 0.42^a	0.93 ± 0.23^a
MKI67	1.19 ± 0.15	1.62 ± 0.26	0.82 ± 0.36^a^,^b	1.03 ± 0.36^a^,^b
MKX	0.47 ± 0.12	0.52 ± 0.13	0.68 ± 0.09^a	0.78 ± 0.14^a^,^b
MMP2	5.37 ± 1.11	7.95 ± 1.53^a	11.2 ± 2.17^a^,^b	11.4 ± 1.57^a^,^b
MMP14	3.24 ± 0.63	5.12 ± 0.44^a	5.36 ± 0.89^a	4.51 ± 0.69^a
PCNA	22.2 ± 4.63	14.3 ± 3.84^a	11.9 ± 1.48^a	13.8 ± 2.61^a
SCX	9.97 ± 2.25	98.9 ± 15.6^a	19.3 ± 7.62^c	265 ± 107^a^,^b
TNMD	30.0 ± 12.9	36.0 ± 3.98	191 ± 80.0^a^,^b	150 ± 37.5^a^,^b

Expression of genes as measured by qPCR. Values are means ± sd.

Differences tested with a 2-way ANOVA (α = 0.05): ^adifferent (P < 0.05) from 7-d Scx:IGF1⁺; ^bdifferent (P < 0.05) from 7-d Scx:IGF1^Δ; ^cdifferent (P < 0.05) from 14-d Scx:IGF1⁺.