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Effects of PKM2 activators on the proliferation of UOK262 cells. UOK262 (FH-WT and FH-deficient) cells were treated with PKM2 activators or DMSO control for the indicated time points. The relative number of viable cells was counted after drug treatments. Data represent means ± sem (n = 3), unpaired, 2-tailed Student’s t test. *P < 0.05, **P < 0.01, ***P < 0.001.
