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Open field test. Although mouse gender and PBS vehicle or OT-58 injections did not show any significant impact on mouse behavior, the REG (filled symbols) and MRD (open symbols) diets resulted in changes in locomotion (A) and anxiety level (B) in both WT (black) and I278T (red) mice. Data points represent results for each individual mouse. Vertical lines delineate minimal and maximal values, whereas horizontal lines designate group mean values. **P < 0.01, ***P < 0.001.
