Figure 8.

Effects of captopril on the decreased bone mass and inhibited osteogenic differentiation induced by PNE in the adult male offspring. A) Representative micro-CT images of the femurs of 12-wk-old offspring. Scale bars, 500 μm. B) Quantitative micro-CT analysis of the trabecular bone microarchitecture. C) qRT-PCR analysis of the gene expression of the osteogenic differentiation markers, including Runx2, BSP, Col1, and OCN in the bone tissue; n = 8/group. Data are expressed as means ± sem. *P < 0.05, **P < 0.01 compared with the controls.