. 2019 Sep 13;33(11):12853–12872. doi: 10.1096/fj.201900057R

TABLE 2.

Mitochondrial respiratory parameters (1.5/0 mT)

Exposure condition	Basal respiration	P	Spare capacity	P	ATP production	P
C2C12 wild type
20 K (plated; n = 9)	1.13 ± 0.15	0.0228^a	1.25 ± 0.25	0.0104^a	1.12 ± 0.12	0.0115^a
30 K (plated; n = 5)	0.91 ± 0.13	0.1207^a	0.89 ± 0.11	0.0608^a	0.96 ± 0.12	0.2671^a
		0.0142^b		0.0075^b		0.02370^b
40 K (suspension-low ρ; n = 4)	1.64 ± 0.29	0.0041^a	1.95 ± 0.48	0.0071^a	1.67 ± 0.31	0.0052^a
40 K (suspension-high ρ; n = 4)	0.91 ± 0.08	0.0694^a	0.88 ± 0.09	0.0499^a	0.92 ± 0.01	0.0895^a
		0.0053^c		0.0091^c		0.0071^c
24 h (n = 2)	1.35 ± 0.08		1.54 ± 0.31		1.29 ± 0.12
48 h (n = 2)	1.09 ± 0.05		1.12 ± 0.17		1.11 ± 0.03
CRISPR/Cas9 TRPC1 knockdown
c60 (n = 4)	0.97 ± 0.14	0.6768^a	0.87 ± 0.24	0.3759^a	0.95 ± 0.15	0.5628^a
c61 (n = 4)	0.95 ± 0.05	0.0582^a	0.90 ± 0.07	0.0462^a	0.93 ± 0.05	0.0482^a
		0.3769^d		0.4104^d		0.4338^d

All values represent means ± SD of n independent experiments. “Suspension-low ρ” and “suspension-high ρ” refer to myoblast suspensions originating from either low- or high-density cultures, respectively, before exposure to PEMFs as indicated and then plated at 40,000 myoblasts/well 6 h before mitochondrial respiratory assessment. P values indicate: ^a0 mT with regard to 1.5 mT; ^b20 K with regard to 30 K; ^clow ρ with regard to high ρ; ^dc60 with regard to c61.