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Effect of CoQ10 on Tac-induced renal tubulointerstitial fibrosis in a rat model. Histologic analysis of renal cortex tissue from rats treated with Tac for 4 wk (A); striped tubulointerstitial fibrosis, mononuclear cell infiltration, and tubular atrophy were observed (B). Renal tissue damage was reduced by CoQ10 treatment. Scale bars, 100 µm. Data represent means ± se (n = 8). One-way ANOVA was used to analyze the data. @P < 0.05 vs. Tac group.
