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. 2019 Nov 29;33(11):11758–11775. doi: 10.1096/fj.201900910R

Figure 8.

Figure 8

Decrease in ACC θ band power and reduction of SFC and phase-locking (between ACC spike and θ phase) following LPC-induced demyelination. A) PSD (including δ, θ, and β bands) of ACC LFP before LPC injection (n = 4 rats) (black color; baseline) and on d 1, 5, 9, and 14 following local LPC injection into ACC region. B) Mean ACC θ band power was decreased at d 5 and 9 after LPC-induced demyelination. C) The SFC distribution of ACC single units (n = 32 neurons and 4 rats) as a function of frequencies recorded at baseline and on d 1, 5, 9, and 14 following local LPC injection into the ACC region. D) Mean SFC values in θ band show reduction of θ band SFC in rats (n = 4) after LPC treatment. E) Mean percentages of phase-locked neurons show a reduction of ACC single-unit spikes phase-locking to the local θ band field potential after LPC treatment (n = 4). *P < 0.05, ***P < 0.001.