Table 2. Updated Aspirin Use and All-Cause, Cancer, GI Cancer, and CRC Mortality Among Individuals Aged 65 Years and Older.
| Reported Aspirin Use | Mortality, Hazard Ratio (95% CI)a | |||
|---|---|---|---|---|
| All-Cause | Cancer | GI Cancer | CRC | |
| None | 1 [Reference] | 1 [Reference] | 1 [Reference] | 1 [Reference] |
| 1-3/mo | 0.84 (0.80-0.88) | 0.87 (0.81-0.94) | 0.84 (0.68-1.05) | 0.90 (0.69-1.19) |
| 1-2/wk | 0.85 (0.81-0.90) | 0.90 (0.82-1.00) | 0.90 (0.68-1.19) | 0.75 (0.50-1.12) |
| ≥3/wk | 0.81 (0.79-0.83) | 0.85 (0.81-0.88) | 0.75 (0.66-0.84) | 0.71 (0.61-0.84) |
Abbreviations: CRC, colorectal cancer; GI, gastrointestinal.
a
Model is additionally adjusted for sex, race/ethnicity, randomization group, smoking status, ibuprofen use 3 or more times per week, and history of myocardial infarction, stroke, hypertension, and diabetes.