Table 1. Patient Characteristics.
Characteristic | No. (%) | P Value | |
---|---|---|---|
SBRT (n = 13 379) | Surgery (n = 91 330) | ||
Age, median (IQR), y | 75 (68-81) | 68 (61-75) | <.001 |
Year of diagnosis | |||
2004-2009 | 1974 (14.8) | 26 730 (29.3) | <.001 |
2010-2015 | 11 405 (85.2) | 64 600 (70.7) | |
Sex | |||
Male | 6065 (45.3) | 42 508 (46.5) | .009 |
Female | 7314 (54.7) | 48 822 (53.5) | |
Race | |||
White | 11 887 (88.9) | 80 521 (88.2) | <.001 |
Black | 1180 (8.8) | 7423 (8.1) | |
Other | 215 (1.6) | 2789 (3.1) | |
Charlson Comorbidity Index score | |||
0 | 6990 (52.3) | 44 097 (48.3) | <.001 |
1 | 3818 (28.5) | 32 968 (36.1) | |
2 or 3 | 2571 (19.2) | 14 265 (15.6) | |
Grade | |||
Well differentiated | 1078 (8.1) | 14 249 (15.6) | <.001 |
Moderately differentiated | 2448 (18.3) | 41 726 (45.7) | |
Poorly differentiated or undifferentiated | 2826 (21.1) | 30 501 (33.4) | |
Unknown | 7027 (52.5) | 4854 (5.3) | |
Histology | |||
Adenocarcinoma | 6522 (48.8) | 58 070 (63.6) | <.001 |
Squamous cell carcinoma | 5143 (38.4) | 27 359 (30.0) | |
Other | 1714 (12.8) | 5901 (6.5) | |
Anatomical site | |||
Right upper lobe | 4448 (33.3) | 31 631 (34.6) | <.001 |
Right middle lobe | 589 (4.4) | 4442 (4.9) | |
Right lower lobe | 2339 (17.5) | 16 302 (17.9) | |
Left upper lobe | 3768 (28.2) | 23 542 (25.8) | |
Left lower lobe | 1940 (14.5) | 12 779 (14.0) | |
Overlapping | 30 (0.2) | 938 (1.0) | |
Lung, not otherwise specified | 214 (1.6) | 1247 (1.4) | |
Other | 51 (0.4) | 449 (0.5) | |
Clinical T stage | |||
T1a | 487 (3.6) | 5759 (6.3) | <.001 |
T1b | 4706 (35.2) | 28 647 (31.4) | |
T1c | 4149 (31.0) | 20 178 (22.1) | |
T2a | 2456 (18.4) | 19 969 (21.9) | |
T2b | 794 (5.9) | 6907 (7.6) | |
T3 | 664 (5.0) | 9706 (10.6) | |
Other | 123 (0.9) | 164 (0.2) | |
Tumor extension | |||
Confined to 1 lung | 9257 (69.2) | 49 026 (53.7) | <.001 |
Adjacent lobe extension | 20 (0.2) | 205 (0.2) | |
Central location | 121 (0.9) | 2693 (3.0) | |
Pleura, chest wall, or diaphragm | 289 (2.2) | 14 061 (15.4) | |
Atelectasis or obstructive pneumonia | 149 (1.1) | 929 (1.0) | |
Unknown | 3543 (26.5) | 24 416 (26.7) | |
Separate nodules in the ipsilateral lung | |||
None | 10 854 (81.1) | 61 160 (67.0) | <.001 |
Same lobe | 297 (2.2) | 2622 (2.9) | |
Different lobes | 0 | 0 | |
Unknown | 2228 (16.7) | 27 548 (30.2) | |
Scope of lymph node surgery | |||
No | 12 750 (95.3) | 7437 (8.1) | <.001 |
Yes | 599 (4.5) | 83 573 (91.5) | |
Unknown | 30 (0.2) | 320 (0.4) | |
Regional lymph nodes examined, No. | |||
0 | 12 238 (91.5) | 7382 (8.1) | <.001 |
1-10 | 371 (2.8) | 50 977 (55.8) | |
11-15 | 17 (0.1) | 14 256 (15.6) | |
>15 | 14 (0.1) | 12 944 (14.2) | |
Other | 739 (5.5) | 5771 (6.3) |
Abbreviations: IQR, interquartile range; SBRT, stereotactic body radiotherapy.