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. 2019 Nov 20;2(11):e1915724. doi: 10.1001/jamanetworkopen.2019.15724

Table 1. Patient Characteristics.

Characteristic No. (%) P Value
SBRT (n = 13 379) Surgery (n = 91 330)
Age, median (IQR), y 75 (68-81) 68 (61-75) <.001
Year of diagnosis
2004-2009 1974 (14.8) 26 730 (29.3) <.001
2010-2015 11 405 (85.2) 64 600 (70.7)
Sex
Male 6065 (45.3) 42 508 (46.5) .009
Female 7314 (54.7) 48 822 (53.5)
Race
White 11 887 (88.9) 80 521 (88.2) <.001
Black 1180 (8.8) 7423 (8.1)
Other 215 (1.6) 2789 (3.1)
Charlson Comorbidity Index score
0 6990 (52.3) 44 097 (48.3) <.001
1 3818 (28.5) 32 968 (36.1)
2 or 3 2571 (19.2) 14 265 (15.6)
Grade
Well differentiated 1078 (8.1) 14 249 (15.6) <.001
Moderately differentiated 2448 (18.3) 41 726 (45.7)
Poorly differentiated or undifferentiated 2826 (21.1) 30 501 (33.4)
Unknown 7027 (52.5) 4854 (5.3)
Histology
Adenocarcinoma 6522 (48.8) 58 070 (63.6) <.001
Squamous cell carcinoma 5143 (38.4) 27 359 (30.0)
Other 1714 (12.8) 5901 (6.5)
Anatomical site
Right upper lobe 4448 (33.3) 31 631 (34.6) <.001
Right middle lobe 589 (4.4) 4442 (4.9)
Right lower lobe 2339 (17.5) 16 302 (17.9)
Left upper lobe 3768 (28.2) 23 542 (25.8)
Left lower lobe 1940 (14.5) 12 779 (14.0)
Overlapping 30 (0.2) 938 (1.0)
Lung, not otherwise specified 214 (1.6) 1247 (1.4)
Other 51 (0.4) 449 (0.5)
Clinical T stage
T1a 487 (3.6) 5759 (6.3) <.001
T1b 4706 (35.2) 28 647 (31.4)
T1c 4149 (31.0) 20 178 (22.1)
T2a 2456 (18.4) 19 969 (21.9)
T2b 794 (5.9) 6907 (7.6)
T3 664 (5.0) 9706 (10.6)
Other 123 (0.9) 164 (0.2)
Tumor extension
Confined to 1 lung 9257 (69.2) 49 026 (53.7) <.001
Adjacent lobe extension 20 (0.2) 205 (0.2)
Central location 121 (0.9) 2693 (3.0)
Pleura, chest wall, or diaphragm 289 (2.2) 14 061 (15.4)
Atelectasis or obstructive pneumonia 149 (1.1) 929 (1.0)
Unknown 3543 (26.5) 24 416 (26.7)
Separate nodules in the ipsilateral lung
None 10 854 (81.1) 61 160 (67.0) <.001
Same lobe 297 (2.2) 2622 (2.9)
Different lobes 0 0
Unknown 2228 (16.7) 27 548 (30.2)
Scope of lymph node surgery
No 12 750 (95.3) 7437 (8.1) <.001
Yes 599 (4.5) 83 573 (91.5)
Unknown 30 (0.2) 320 (0.4)
Regional lymph nodes examined, No.
0 12 238 (91.5) 7382 (8.1) <.001
1-10 371 (2.8) 50 977 (55.8)
11-15 17 (0.1) 14 256 (15.6)
>15 14 (0.1) 12 944 (14.2)
Other 739 (5.5) 5771 (6.3)

Abbreviations: IQR, interquartile range; SBRT, stereotactic body radiotherapy.