Figure 5.

Podocyte‐specific knockout of GSK3α is not protective in in vivo and in vitro Adriamycin injury models. A, Body weights of Adriamycin‐treated mice. (B) Urinary albumin:creatinine in Adriamycin‐treated mice showing increased albuminuria in both podGSK3αKD and control mice at 1 and 2 wk. t test **P < 0.01. C, Representative images of ciGSK3αKO and non‐transduced control cells treated with Adriamycin for 24 h. D, Cell survival is identical in ciGSK3αKO and control cells treated with Adriamycin for 24 h. n = 3 experiments