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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Cell Immunol. 2019 Oct 26;346:103997. doi: 10.1016/j.cellimm.2019.103997

Fig. 4.

Fig. 4.

Liver pathology following adoptive transfer. Mice received i.v. injections of the vector and, 14 days later, OT-1 CD8+ T cells were transferred concurrent with an administration of 40 μg CpG ODN. Mice were sacrificed on days three, seven, and 14 following adoptive transfer. We stained liver sections for H&E and scored for extent of (A) inflammation, (B) hepatocellular necrosis, (C) hepatocellular regeneration, and (D) oval-cell hyperplasia. (E) The histopathologic images depicted represent general trends for each dose group. Statistical analysis by student t test. *P < 0.05, **P < 0.001, ***P < 0.0001. ****P < 0.00001. Error Bars = SEM.