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. 2019 Dec 10;14(12):e0226150. doi: 10.1371/journal.pone.0226150

Fig 1. Flow-chart of inclusion vs. exclusion in the study cohort.

Fig 1

In analysis, 36 patients with a local/regional recurrence of BC1 before diagnosis of BC2 were excluded in order not to confuse the results by eventual treatment given for the recurrence. We also excluded 3 patients with ambiguous distant metastasis-status and 1 patient with BC2 diagnosed at autopsy.