Table II.
Outcome of the FAS population at the 2-year follow-up.
| Weight reduction and IVF group | IVF only group | p-value odds ratio (95%CI) | |
|---|---|---|---|
| Cumulative live birth rate * | 87/152 (57.2) | 82/153 (53.6) | 0.56 1.16 (0.74 to 1.52) |
| No. of participants in the follow-up | 137 | 139 | |
| No. of additional live births after index cycle | 42 | 40 | |
| Additional live birth rate | 42/137 (30.7) | 40/139 (28.8) | |
| Way of conception | |||
| IVF/ICSI | 20/42 (47.6) | 20/40 (50) | |
| FET | 11/42 (26.2) | 9/40 (22.5) | |
| Spontaneous pregnancies | 9/42 (21.4) | 9/40 (22.5) | |
| Oocyte donation/ | 1/42 (2.4) | 0 (0.0) | |
| Gonadotrophin stimulation | 1/42 (2.4) | 0 (0.0) | |
| Unknown | 0 (0.0) | 2/40 (5.0) | |
| Ongoing pregnancies | 19 | 16 | |
| ‐ Expecting first child in the study | 10/137 (7.3) | 7/139 (5.0) | |
| ‐ Expecting second child in the study | 9/137 (6.6) | 9/139 (6.5) | |
| Way of conception | |||
| IVF/ICSI | 6/19 (31.6) | 4/16 (25.0) | |
| FET | 4/19 (21.1) | 1/16 (6.3) | |
| Spontaneous pregnancy | 9/19 (47.4) | 9/16 (56.3) | |
| Oocyte donation/ | 0 (0.0) | 1/16 (6.3) | |
| Unknown | 0 (0.0) | 1/16 (6.3) | |
| Cumulative live birth rate/ongoing pregnancy rate | 97/152 (63.8) | 89/153 (58.2) | 0.34 1.28 (0.8 to 2.01) |
| Total no. of started IVF/ICSI cycles ** | 214 | 244 | |
| Total no. of FET ** | 70 | 74 |
FAS: full analysis set, FET: frozen embryo transfer.
For categorical variables, n (%) is presented.
For comparison between groups, Fisher’s Exact test (lowest 1-sided p-value multiplied by 2) was used for dichotomous variables.
*Cumulative live birth defined as at least one child born alive. Calculated on all FAS patients 152/153.
**Missing data from one Danish clinic concerning any follow-up treatments performed by the nine patients in the weight reduction and IVF group and the seven patients from the IVF-only group.