Table 2.
SNP | Allele frequency | Beta | SE | p-value |
---|---|---|---|---|
B_801 | 0.143 | 4.3 × 10 –4 | 9.4 × 10 –5 | 3.9 × 10 –6 |
DRB1_301 | 0.147 | 3.7 × 10 –4 | 9.2 × 10 –5 | 5.6 × 10 –5 |
DRB3_9901 | 0.655 | −2.6 × 10–4 | 6.9 × 10–5 | 1.5 × 10–4 |
DRB3_101 | 0.166 | 3.3 × 10 –4 | 8.8 × 10 –5 | 2.0 × 10 –4 |
DQA1_501 | 0.230 | 2.9 × 10 –4 | 7.8 × 10 –5 | 2.1 × 10 –4 |
C_701 | 0.175 | 3.2 × 10 –4 | 8.6 × 10 –5 | 2.4 × 10 –4 |
DQB1_201 | 0.148 | 3.4 × 10 –4 | 9.2 × 10 –5 | 2.7 × 10 –4 |
The table shows the allele frequencies, beta, standard error and p values of all classical HLA alleles with a p value below 5 × 10–4 [computed through Bolt-LMM] and MAF > 0.01. SNPs in bold are part of the HLA A1-B8-DR3-DQ2 [ancestral MHC 8.1] haplotype.