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. 2019 May 24;13(12):1578–1582. doi: 10.1093/ecco-jcc/jjz104

Table 2.

Classical HLA alleles

SNP Allele frequency Beta SE p-value
B_801 0.143 4.3 × 10 –4 9.4 × 10 –5 3.9 × 10 –6
DRB1_301 0.147 3.7 × 10 –4 9.2 × 10 –5 5.6 × 10 –5
DRB3_9901 0.655 −2.6 × 10–4 6.9 × 10–5 1.5 × 10–4
DRB3_101 0.166 3.3 × 10 –4 8.8 × 10 –5 2.0 × 10 –4
DQA1_501 0.230 2.9 × 10 –4 7.8 × 10 –5 2.1 × 10 –4
C_701 0.175 3.2 × 10 –4 8.6 × 10 –5 2.4 × 10 –4
DQB1_201 0.148 3.4 × 10 –4 9.2 × 10 –5 2.7 × 10 –4

The table shows the allele frequencies, beta, standard error and p values of all classical HLA alleles with a p value below 5 × 10–4 [computed through Bolt-LMM] and MAF > 0.01. SNPs in bold are part of the HLA A1-B8-DR3-DQ2 [ancestral MHC 8.1] haplotype.