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. 2019 May 24;13(12):1578–1582. doi: 10.1093/ecco-jcc/jjz104

Table 4.

Nominally significant SNPs in Crohn’s disease and IBD GRS

GRS Chromosome Position A1 A1 frequency Beta SE p
Both 10 6081230 C 0.836092 2.2 × 10–4 8.85 × 10–5 1.4 × 10–2
Both 2 28614794 C 0.519615 1.5 × 10–4 6.58 × 10–5 1.9 × 10–2
Both 22 30493882 G 0.55509 1.8 × 10–4 6.58 × 10–5 7.7 × 10–3
Both 17 32593665 A 0.72546 1.6 × 10–4 7.32 × 10–5 3.0 × 10–2
Both 21 45615741 G 0.394392 1.3 × 10–4 6.69 × 10–5 4.7 × 10–2
Both 7 50175654 G 0.573233 −1.7 × 10–4 6.62 × 10–5 1.2 × 10–2
Both 7 50304461 C 0.33364 −1.4 × 10–4 6.94 × 10–5 4.1 × 10–2
Crohn’s disease 12 6491125 G 0.646309 −1.6 × 10–4 6.93 × 10–5 1.8 × 10–2
IBD 7 2869985 T 0.697662 2.3 × 10–4 7.12 × 10–5 1.1 × 10–3
IBD 13 27531267 T 0.82362 2.2 × 10–4 8.58 × 10–5 1.1 × 10–2

Summary statistics of the known risk variants for Crohn’s disease and IBD in our microscopic colitis genome-wide association study for those that pass the nominal p value threshold of 0.05. Abbreviation: IBD, inflammatory bowel disease; GRS, genetic risk score.