Table 4.
GRS | Chromosome | Position | A1 | A1 frequency | Beta | SE | p |
---|---|---|---|---|---|---|---|
Both | 10 | 6081230 | C | 0.836092 | 2.2 × 10–4 | 8.85 × 10–5 | 1.4 × 10–2 |
Both | 2 | 28614794 | C | 0.519615 | 1.5 × 10–4 | 6.58 × 10–5 | 1.9 × 10–2 |
Both | 22 | 30493882 | G | 0.55509 | 1.8 × 10–4 | 6.58 × 10–5 | 7.7 × 10–3 |
Both | 17 | 32593665 | A | 0.72546 | 1.6 × 10–4 | 7.32 × 10–5 | 3.0 × 10–2 |
Both | 21 | 45615741 | G | 0.394392 | 1.3 × 10–4 | 6.69 × 10–5 | 4.7 × 10–2 |
Both | 7 | 50175654 | G | 0.573233 | −1.7 × 10–4 | 6.62 × 10–5 | 1.2 × 10–2 |
Both | 7 | 50304461 | C | 0.33364 | −1.4 × 10–4 | 6.94 × 10–5 | 4.1 × 10–2 |
Crohn’s disease | 12 | 6491125 | G | 0.646309 | −1.6 × 10–4 | 6.93 × 10–5 | 1.8 × 10–2 |
IBD | 7 | 2869985 | T | 0.697662 | 2.3 × 10–4 | 7.12 × 10–5 | 1.1 × 10–3 |
IBD | 13 | 27531267 | T | 0.82362 | 2.2 × 10–4 | 8.58 × 10–5 | 1.1 × 10–2 |
Summary statistics of the known risk variants for Crohn’s disease and IBD in our microscopic colitis genome-wide association study for those that pass the nominal p value threshold of 0.05. Abbreviation: IBD, inflammatory bowel disease; GRS, genetic risk score.