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(A) A titanium tibial implant for the mice is shown. (B) After the wound was surgically closed, an inoculation of Staphylococcus aureus was applied to the joint space. (C) An example radiograph of an animal with resistance to infection and intact bone-implant interface is shown on the left and a radiograph of a mouse with infection is shown on the right illustrating bone loss around the implant (arrow).
