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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Ann Thorac Surg. 2019 Jun 20;108(3):828–836. doi: 10.1016/j.athoracsur.2019.04.099

Table 3.

Multivariable Analysis of Factors Associated with Administration of Adjuvant Therapy

Variable Multivariable OR (95% CI) p-value
Age 0.97 (0.95–0.98) <0.001
Post-Treatment Pathologic Stage <0.001
IIB (reference)
IIIA 1.80 (1.12–2.90)
IIIB 0.98 (0.56–1.72)
IIIC 2.74 (1.53–4.90)
Tumor Grade 0.04
1 (reference)
2 1.01 (0.33–3.12)
3 0.90 (0.30–2.73)
4 1.20 (0.33–4.34)
X 0.39 (0.12–1.27)
Neoadjuvant Radiation 0.40 (0.21–0.75) 0.004
Smoking 0.63 (0.42–0.96) 0.03
Pneumonia 0.45 (0.23–0.90) 0.02
UTI 0.05 (0.01–0.40) 0.005

Multilevel random-intercept (site) analysis was performed to account for practice patterns between institutions. The intraclass correlation coefficient (ICC) was 0.359, meaning 35.9% of the variation in adjuvant treatment administration is accounted for by institutional effect.