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. Author manuscript; available in PMC: 2019 Dec 10.
Published in final edited form as: Cell Rep. 2019 Nov 26;29(9):2570–2578.e5. doi: 10.1016/j.celrep.2019.10.073

Figure 3. Global Analysis Reveals Enhancer-Driven Regulatory Networks (ERNs).

Figure 3.

(A) Genome Browser snapshots illustrate the local epigenetic features of several targeted enhancers near LMO2, NFE2, and MYB/AHI1.

(B) Similar to Figure 1G. In addition, the dot size represents fold change.

(C) An enhancer-driven regulatory network (ERN) consists of an enhancer’s primary (direct) targets and its secondary (indirect) targets.

(D) An example ERN.

(E) ERN sub-network highlighting PTRF, CD24, and VIM as common secondary targets of enhancers across the genome.

See also Figure S3 and Table S4.