Table 3.

Observed and estimated HbA1c concentrations during the study period

	Baseline	6 months	12 months	Difference (12 months)
All patients
Observed	62 (55 to 72)	58 (52 to 65)	58 (52 to 66)
Number	1362	790	687
Estimated	64.1 (62.5 to 64.9)	59.2 (58.4 to 60.2) **	60.1 (59.2 to 61.1) **	−4.0 (–5.5 to –2.6)
T1DM
Observed	62 (54 to 71)	57 (51 to 65)	58 (53 to 66)
Number	1051	628	543
Estimated	63.5 (62.7 to 64.3)	59.2 (58.2 to 60.1) **	60.2 (59.1 to 61.3) **	−3.3 (–4.9 to –1.7)
T2DM
Observed	67 (56 to 78)	61 (53 to 67)	62 (53 to 69)
Number	223	114	99
Estimated	68.2 (66.3 to 70.8)	61.2 (58.6 to 63.8) **	62.0 (59.2 to 64.7) *	−6.2 (–10.3 to –2.1)
Other forms of DM
Observed	61 (51 to 71)	57 (51 to 63)	55 (50 to 62)
Number	88	48	45
Estimated	62.2 (59.6 to 64.8)	56.1 (52.6 to 59.6)*	56.2 (52.6 to 59.8) *	−6.0 (–11.5 to –0.6)

Values are presented as numbers, medians (25th, 75th centiles) and estimated means (difference) (95% CI). Data are presented as observed data and estimated data using the linear mixed model. HbA1c concentrations are presented in mmol/mol.

*p<0.05 as compared with baseline; **p<0.001 as compared with baseline.

DM, diabetes mellitus; T1DM, type I diabetes mellitus; T2DM, type II diabetes mellitus.