Skip to main content
. 2019 Nov 27;8:e53400. doi: 10.7554/eLife.53400

Video 1. Conformational changes of the HCN1 voltage sensor during activation.

Download video file (2.1MB, mp4)

The S4 helix is shown in cyan, its positively charged residues in different colors (K261 purple, R267 cyan, R270 green, R273 orange and R276 red). The hydrophobic plug (F186) is colored in light green. S3 is gray and the rest of the voltage sensor is transparent.