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. 2019 Dec 4;10:2763. doi: 10.3389/fmicb.2019.02763

TABLE 2.

Result of D-test obtained with MRSA and MSSA isolates showing presence of erythromycin resistance genes and its correlation with MLSB phenotypes among Staphylococcus aureus.

Erythromycin resistance and MSB phenotypes Phenotype (%) Gene combinations

msrA ermA ermC mphC msrA, ermC ermA, ermC ermC, mphC msrA, ermA, ermC msrA, ermC, mphC msrA, ermA, ermC, mphC
MRSA (n=32)
ER-S, CL-S 10 (31.25%) 0 0 0 0 3 (30%) 0 1 (10%) 1 (10%) 3 (30%) 1 (10%)
ER-R, CL-S (MSB phenotype) 2 (6.25%) 0 0 0 0 1 (50%) 0 0 0 1 (50%) 0
ER-R, CL-R (cMLSB phenotype) 6 (18.75%) 0 0 1 (16.6 %) 0 0 3 (50%) 1 (16.6%) 0 1 (16.6%) 0
ER-R, CL-D (iMLSB phenotype) 10 (31.25%) 0 0 6 (60%) 0 0 1 (10%) 0 1 (10%) 1 (10%) 0
MSSA (n=77)
ER-S, CL-S 52 (67.5%) 3 (5.7%) 1 (1.9%) 16 (30.7 %) 1 (1.9%) 20 (38.4%) 0 4 (7.6%) 0 4 (7.6%) 0
ER-R, CL-S (MSB phenotype) 12 (15.5%) 0 1 (8.3%) 1 (8.3%) 2 (16.6 %) 6 (50%) 0 0 0 0 0
ER-R, CL-R (cMLSB phenotype) 1 (1.29%) 0 0 0 0 0 0 0 1 (100%) 0 0
ER-R, CL-D (iMLSB phenotype) 4 (5.19%) 0 0 1 (25%) 0 3 (75%) 0 0 0 0 0

S: sensitive; R: resistance; ER: erythromycin; CL: clindamycin.