Figure 4.

MSP2 cross-reactive and allele-specific responses induced by vaccination or acquired through natural malaria exposure. MSP2 antibody responses from vaccine trial recipients (Vaccine; n = 16) and individuals with naturally acquired antibodies (Mugil; n = 18) were tested in competition enzyme-linked immunosorbent assay (ELISA) and the percentage of response that was cross-reactive and allele specific was calculated. Data from tested selected individual samples are presented in Supplementary Figure 5. P values were calculated using the Wilcoxon matched-pairs signed rank test.