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. 2019 Dec 4;10:1208. doi: 10.3389/fgene.2019.01208

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Copyright © 2019 Ni, Zhou, Aslam and Niu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Clear differences in the Gene Ontology enrichment between most reliable dosage-sensitive (MRDS) transcription factors (TFs) and most reliable dosage-insensitive (MRDIS) TFs. Due to space limitations, only the most significant terms of the MRDS TFs are displayed. The color of each circle represents the significance of the enrichment adjusted using the Benjamini-Hochberg (BH) procedure and the size of each circle represents the percentage of genes associated with that term.