Table 4.

Differences in the protein expression patterns of the most reliable dosage-sensitive (MRDS) transcription factors (TFs) and most reliable dosage-insensitive (MRDIS) TFs.

	MRDS genes	MRDIS genes	p	MRDS TFs	MRDIS TFs	p
Number of genes	684	2736		92	150
Number of cell samples in which the proteins are
at high levels	4.5 ± 6.6	3.1 ± 4.8	<10−6	4.6 ± 6.6	3.8 ± 5.4	0.520
at medium levels	9.2 ± 6.6	7.6 ± 6.7	<10−6	9.3 ± 7.2	9.8 ± 6.2	0.416
at low levels	5.9 ± 4.3	4.8 ± 4.2	<10−6	5.4 ± 4.3	6.2 ± 4.4	0.116
not detected	11.3 ± 9.9	15.5 ± 11.1	<10−6	11.8 ± 10.8	11.1 ± 9.5	0.960

In total, 31 cell samples were studied for each gene. The MRDS genes and the MRDIS genes are defined in Tables 1 and 2 as well as in the main text. The p values were calculated using Mann-Whitney U tests.