Table 2.
Treatment‐emergent AEs of all grades occurring in ≥15% of all patients
| AE, n (%) | FL | All DLBCL | All | |||
|---|---|---|---|---|---|---|
| n = 27 | n = 34a | n = 61 | ||||
| All Grades | Grade 3/4 | All Grades | Grade 3/4 | All Grades | Grade 3/4 | |
| Diarrhea | 16 (59) | 1 (4) | 16 (47) | 1 (3) | 32 (52) | 2 (3) |
| Fatigue | 12 (44) | 1 (4) | 16 (47) | 4 (12) | 28 (46) | 5 (8) |
| Nausea | 9 (33) | 0 | 12 (35) | 1 (3) | 21 (34) | 1 (2) |
| Peripheral edema | 7 (26) | 1 (4) | 13 (38) | 3 (9) | 20 (33) | 4 (7) |
| Decreased appetite | 8 (30) | 0 | 11 (32) | 1 (3) | 19 (31) | 1 (2) |
| Neutropenia | 6 (22) | 4 (15) | 11 (32) | 9 (26) | 17 (28) | 13 (21) |
| Vomiting | 5 (19) | 0 | 12 (35) | 0 | 17 (28) | 0 |
| Upper respiratory tract infection | 12 (44) | 0 | 3 (9) | 0 | 15 (25) | 0 |
| Cough | 8 (30) | 0 | 6 (18) | 0 | 14 (23) | 0 |
| Dyspnea | 6 (22) | 2 (7) | 8 (24) | 4 (12) | 14 (23) | 6 (10) |
| Rash maculopapular | 6 (22) | 3 (11) | 7 (21) | 1 (3) | 13 (21) | 4 (7) |
| Back pain | 6 (22) | 1 (4) | 5 (15) | 0 | 11 (18) | 1 (2) |
| Pyrexia | 3 (11) | 0 | 8 (24) | 2 (6) | 11 (18) | 2 (3) |
| Constipation | 3 (11) | 0 | 7 (21) | 0 | 10 (16) | 0 |
| Dry mouth | 4 (15) | 0 | 6 (18) | 0 | 10 (16) | 0 |
| Hyperuricemia | 5 (19) | 1 (4) | 5 (15) | 1 (3) | 10 (16) | 2 (3) |
| Insomnia | 4 (15) | 0 | 6 (18) | 0 | 10 (16) | 0 |
| Thrombocytopenia | 4 (15) | 0 | 6 (18) | 2 (6) | 10 (16) | 2 (3) |
| Dizziness | 3 (11) | 1 (4) | 6 (18) | 0 | 9 (15) | 1 (2) |
| Increased tendency to bruise | 5 (19) | 0 | 4 (12) | 0 | 9 (15) | 0 |
| Muscle spasms | 6 (22) | 0 | 3 (9) | 0 | 9 (15) | 0 |
Abbreviations: AE, adverse event; DLBCL, diffuse large B‐cell lymphoma; FL, follicular lymphoma.
a
Includes patients with GCB DLBCL, non‐GCB DLBCL, and unspecified DLBCL.