TABLE 1.
Patient Characteristics and Comprehensive VTE Chemoprophylaxis Failure Rates
| Patient Characteristic | Patients n (%) | Any VTE Chemoprophylaxis Failure* n (%) | P Value† |
|---|---|---|---|
| Overall | 4086 (100) | 734 (18.0) | |
| Age | 0.49 | ||
| ≤40 yrs | 351 (8.6) | 100 (28.5) | |
| 41–60 yrs | 1,378 (33.7) | 256 (18.6) | |
| 61–74 yrs | 1430 (35.0) | 223 (15.6) | |
| ≥75 yrs | 927 (22.7) | 155 (16.7) | |
| Sex | 0.85 | ||
| Male | 1911 (46.8) | 352 (18.4) | |
| Female | 2175 (53.2) | 382 (17.6) | |
| Race | 0.58 | ||
| Asian | 103 (2.5) | 15 (14.6) | |
| African American | 482 (11.8) | 127 (26.3) | |
| White | 3294 (80.6) | 553 (16.8) | |
| Other/unknown | 207 (5.1) | 39 (18.8) | |
| Body Mass Index | 0.79 | ||
| Underweight | 141 (3.5) | 34 (24.1) | |
| Normal | 1172 (28.7) | 226 (19.3) | |
| Overweight/obese | 2773 (67.9) | 474 (17.1) | |
| Diabetes | 0.77 | ||
| Yes | 637 (15.6) | 105 (16.5) | |
| No | 3449 (84.4) | 629 (18.2) | |
| Comorbidities | 0.96 | ||
| 0 | 985 (24.1) | 157 (15.9) | |
| 1 | 1406 (34.4) | 257 (18.3) | |
| 2 | 905 (22.2) | 174 (19.2) | |
| ≥3 | 790 (19.3) | 146 (18.5) | |
| Active smoker | 0.98 | ||
| Yes | 746 (18.3) | 135 (18.1) | |
| No | 3340 (81.7) | 599 (17.9) | |
| Surgical indication | 0.28 | ||
| Neoplasm | 1935 (47.4) | 299 (15.5) | |
| Benign | 2151 (52.6) | 435 (20.2) | |
| Elective surgery | 0.19 | ||
| Yes | 2741 (67.1) | 437 (15.9) | |
| No | 1345 (32.9) | 297 (22.1) | |
| Length of Stay (LOS) | 0.15 | ||
| Quartile 1 (≤3 d) | 957 (23.4) | 105 (11.0) | |
| Quartile 2 (4–5 d) | 1239 (30.3) | 207 (16.7) | |
| Quartile 3 (6–8 d) | 974 (23.8) | 185 (19.0) | |
| Quartile 4 (≥9 d) | 915 (22.4) | 237 (25.9) | |
| Median LOS, d (IQR) | 5 (4–8) | ||
*
Patients that failed comprehensive VTE chemoprophylaxis for any reason. The percentage is out of the total patients in the corresponding subgroup.
†
Clustered chi-square test of association.