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. 2019 Dec 10;9:18686. doi: 10.1038/s41598-019-55337-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Community distribution of the faecal microbiota based on 16 s rRNA gene surveys. (a) Alpha diversity was applied to analyse the complexity of species of the NC, HTH, and PR groups. Indices of Chao1, Shannon, and Simpson are displayed. (b) Principal component analysis (PCA) at the Operational Taxonomic Units (OUT) level. The PCA of all the samples was based on the relative abundance of the OTUs. Numbers in brackets represent the contributions of principal components to differences among samples. (c) The abundance of the different phyla, and (d) different families in all samples was shown. “*”: Phyla and families with different abundance are highlighted in black. (e) A heat map showing the taxonomic composition distribution among samples at the genus-level. (f) Five bacterial genera are identified with significant different abundance among groups.