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. 2019 Dec 10;8(12):73. doi: 10.1038/s41389-019-0182-7

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a qRT-PCR showing the relative levels of MACC1-AS1 in breast cancer cell lines. b, c qRT-PCR results indicate the expression of MACC1-AS1 in MACC1-AS1-overexpressing (MDA-MB-231) and knockdown (BT546) cells. d, e MTT assays were used to measure proliferation in MACC1-AS1-overexpressing and -knockdown cells. *P < 0.01. f Representative tumor samples and statistical analyses of tumor volumes in two xenograft groups are shown. Tumors derived from MDA-MB-231/MACC1-AS1 cells displayed larger primary tumor masses. *P < 0.05. g Representative images and statistical analyses indicate the invasiveness of MACC1-AS1-overexpressing MDA-MB-231 and control cells. **P < 0.01.