Fig. 1. Circ_0001955 was found to be upregulated in HCC.
a–c Volcano plots indicate dysregulated circRNAs between HCC and normal samples from the GSE7852, GSE94508 and GSE97322 datasets. d Venn diagram showing the intersection. e Relative fold changes of circ_0038718, circ_0001955 and circ_0072088. f Relative expression level of circ_0001955 was analyzed by qRT-PCR in tumor and adjacent normal specimens from HCC patients, *P < 0.05. g Serum circ_0001955 level was examined by qRT-PCR in healthy control and HCC patients, ***P < 0.001. h Serum circ_0001955 level of HCC patients before and after surgery, ***P < 0.001. i qRT-PCR analysis of circ_0001955 in the normal hepatocyte LO2 cell line and HCC cell lines (Huh-7, HepG2, SMMC-7721, Bel-7402, and Hep-3B).