Figure 5.

Results of Downsampling Experiments

(A) Shown are the number of genes significant in each downsampling test from the discovery cohort. In blue are those from downsamplings consisting of males only and in purple are downsamplings from males and females. The red line indicates the actual result of the female set.

(B) Fraction of individuals with DD versus the fraction of females in each downsampling set.

(C) Number of significant genes versus the fraction of females in each downsampling set.

(D) Number of significant genes versus the fraction of individuals in the discovery cohort with DD.

Above the plots for (B), (C), and (D) are the results of the correlation test.