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Microparticle SEM and in vitro release kinetics. A-C) Dried d-AmB/PLGA microparticles were imaged by SEM in lower (A) and higher (B) magnification to confirm absence external AmB. Dry AmB (C) is shown as control. D) d-AmB/PLGA microparticles were incubated in duplicate at 37 °C in PBS under mild agitation. At the indicated times, supernatant samples were removed for quantification of AmB by HPLC, followed by PBS volume replacement. Means ± SD (n = 2).
