Fig. 6.

Systemic toxicology. Thirty-day infected mice were given a single dose of the indicated AmB formulations or controls, as for Fig. 4. After sixty days of treatment, sera were collected and individually assayed for AST (A), ALT (B), and creatinine (C). Positive control (1% of CCl₄) was given by intraperitoneal injection on day 87. Means ± SD (n = 5).