Fig. 2.

Comparison of mutations in T. annulata Cytochrome b and TaPIN1 genes.

a. Schematic representation of the number of isolates with mutation in the Cyt b or Pin1 gene and the number of isolates with mutations in both genes.

b. Details of the number of isolates identified with mutations at each position. The number of isolates with only TaPIN1 mutations (right) or with mutations in both genes (center).

c. Sequence alignment of Pin1 proteins in H. sapiens, M. musculus, T. orientalis, T. equi, T. parva or T. annulata showing the predicted signal peptide (boxed) in TaPin1 and TpPin1 and the positions of each mutation identified in this study.